The effect of farnesol on amino acid incorporation by a wild-type and cell-wall variant strain of Candida albicans

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Abstract

Farnesol, a quorum sensing (QS) signal, is produced by Candida albicans during high density growth and has been found to inhibit morphogenesis. This QS auto-inducing signal was discovered to increase amino acid incorporation by C. albicans when concentrations of farnesol increased to 10 µg/mL in yeast nitrogen broth. Farnesol concentrations greater than 10 µg/mL abolished the enhanced incorporation, and the magnitude of the increased incorporation was dependent on cell-surface hydrophobicity. Key words: Candida albicans , farnesol, amino acid incorporation.

Original languageAmerican English
JournalCanadian Journal of Microbiology
Volume51
DOIs
StatePublished - Jan 1 2005

Keywords

  • Candida albicans
  • farnesol
  • amino acid incorporation

Disciplines

  • Biology
  • Life Sciences

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