The development of endoselective epoxide-opening cascades in water

C. J. Morten; J. A. Byers; Aaron R. Van Dyke; I. Vilotijevic; T. F. Jamison; Aaron R. VanDyke

doi:10.1039/B816697H

The development of endoselective epoxide-opening cascades in water

C. J. Morten, J. A. Byers, Aaron R. Van Dyke, I. Vilotijevic, T. F. Jamison, Aaron R. VanDyke

Fairfield University

Fairfield University

Research output: Contribution to journal › Article › peer-review

Abstract

This tutorial review traces the development of endo-regioselective epoxide-opening reactions in water. Templated, water-promoted epoxide-opening cyclization reactions can offer rapid access to subunits of the ladder polyethers, a fascinating and complex family of natural products. This review may be of interest to those curious about the ladder polyethers and their hypothesized biogenesis, about organic reactions in water, and about the development and application of cascade reactions in organic synthesis.

Original language	American English
Journal	Chemical Society Reviews
Volume	39
DOIs	https://doi.org/10.1039/B816697H
State	Published - Jan 1 2009

Disciplines

Chemistry
Physical Sciences and Mathematics

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10.1039/B816697HLicense: CC BY

Cite this

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abstract = " This tutorial review traces the development of endo-regioselective epoxide-opening reactions in water. Templated, water-promoted epoxide-opening cyclization reactions can offer rapid access to subunits of the ladder polyethers, a fascinating and complex family of natural products. This review may be of interest to those curious about the ladder polyethers and their hypothesized biogenesis, about organic reactions in water, and about the development and application of cascade reactions in organic synthesis.",

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The development of endoselective epoxide-opening cascades in water

Abstract

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