TY - JOUR
T1 - Short communication
T2 - Diffusion tensor anisotropy in the cingulate in borderline and schizotypal personality disorder
AU - Goldstein, Kim E.
AU - Haznedar, M. Mehmet
AU - Alloy, Lauren B.
AU - Drabick, Deborah A.G.
AU - McClure, Margaret M.
AU - New, Antonia S.
AU - Chu, King Wai
AU - Vaccaro, Daniel
AU - Tang, Cheuk Y.
AU - Meyerson, David
AU - Hazlett, Erin A.
N1 - Publisher Copyright:
© 2019
PY - 2019/9
Y1 - 2019/9
N2 - Despite considerable phenomentological differences between borderline personality disorder (BPD) and schizotypal personality disorder (SPD), research increasingly provides evidence that some BPD symptoms overlap with SPD symptoms (e.g., disturbed cognitions). We examined the cingulate, a brain region implicated in the pathophysiology of both disorders, to determine similarities/differences between the groups, and similarities/differences from healthy controls (HC's). 3T structural and diffusion tensor magnetic resonance imaging scans were acquired in BPD (n = 27), SPD (n = 32), HC's (n = 34). Results revealed that BPD patients exhibited significantly lower FA in posterior cingulate white matter compared to HC's (p = 0.04), but SPD patients did not.
AB - Despite considerable phenomentological differences between borderline personality disorder (BPD) and schizotypal personality disorder (SPD), research increasingly provides evidence that some BPD symptoms overlap with SPD symptoms (e.g., disturbed cognitions). We examined the cingulate, a brain region implicated in the pathophysiology of both disorders, to determine similarities/differences between the groups, and similarities/differences from healthy controls (HC's). 3T structural and diffusion tensor magnetic resonance imaging scans were acquired in BPD (n = 27), SPD (n = 32), HC's (n = 34). Results revealed that BPD patients exhibited significantly lower FA in posterior cingulate white matter compared to HC's (p = 0.04), but SPD patients did not.
KW - Borderline personality disorder
KW - Diffusion tensor imaging
KW - Schizotypal personality disorder
UR - https://www.scopus.com/pages/publications/85065539967
UR - https://www.scopus.com/pages/publications/85065539967#tab=citedBy
U2 - 10.1016/j.psychres.2019.05.016
DO - 10.1016/j.psychres.2019.05.016
M3 - Article
C2 - 31101379
AN - SCOPUS:85065539967
SN - 0165-1781
VL - 279
SP - 353
EP - 357
JO - Psychiatry Research
JF - Psychiatry Research
ER -